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KMID : 0361020010440010116
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Korean Journal of Otolaryngology - Head and Neck Surgery
2001 Volume.44 No. 1 p.116 ~ p.118
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A Case of Concurrent Medullary and Papillary Carcinoma of the Thyroid Gland
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Abstract
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The simultaneous occurrence of two distinct neoplasms derived from different cells of origin is sometimes recognized. In the thyroid gland, two such distinct tumors could consist of a concurrent medullary carcinoma composed of parafollicular C
cells and
well-differentiated carcinoma showing follicular epithelial cell differentiation. We report a rare, interesting case of concurrent medullary and papillary carcinoma of the thyroid gland. A 53-year-old female underwent total thyroidectomy and
central
neck dissection for medullary carcinoma of the left lobe of the thyroid gland, which was diagnosed by fine needle aspiration cytology and a high level of calcitonin. The left lobe showed a medullary carcinoma. the right lobe incidentally showed
an
papillary microcarcinoma. Two lymph nodes contain metastasis of medullary carcinoma. The two different tumor cells revealed the characteristic features of each on the microscopic, histochemical findings. We report a case of concurrent medullary
and
papillary carcinoma of the thyroid gland, with a review of the previously reported literature.
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KEYWORD
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